Phosphono-carboxylate compounds for treating amyloidosis

Therapeutic compounds and methods for modulating amyloid deposition in a subject, whatever its clinical setting, are described. Amyloid deposition is modulated by the administration to a subject of an effective amount of a therapeutic compound comprising a phosphonate group and a carboxylate group,...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	THATCHER GREGORY R.J, SZAREK WALTER A, KONG XIANQI, GORINE BORIS
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

container_end_page
container_issue
container_start_page
container_title
container_volume
creator	THATCHER GREGORY R.J SZAREK WALTER A KONG XIANQI GORINE BORIS
description	Therapeutic compounds and methods for modulating amyloid deposition in a subject, whatever its clinical setting, are described. Amyloid deposition is modulated by the administration to a subject of an effective amount of a therapeutic compound comprising a phosphonate group and a carboxylate group, a congener thereof, or a pharmaceutically acceptable salt or ester thereof. In preferred embodiments, an interaction between an amyloidogenic protein and a basement membrane constituent is modulated.
format	Patent
fullrecord	<record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US2001027186A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US2001027186A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US2001027186A13</originalsourceid><addsrcrecordid>eNrjZLAIyMgvLsjIz8vXTU4sSsqvqMxJLElVSM7PLcgvzUspVkjLL1IoKUpNLMnMS1dIzK3Myc9MyS_OLOZhYE1LzClO5YXS3AzKbq4hzh66qQX58anFBYnJqXmpJfGhwUYGBoYGRuaGFmaOhsbEqQIAPzEwPA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Phosphono-carboxylate compounds for treating amyloidosis</title><source>esp@cenet</source><creator>THATCHER GREGORY R.J ; SZAREK WALTER A ; KONG XIANQI ; GORINE BORIS</creator><creatorcontrib>THATCHER GREGORY R.J ; SZAREK WALTER A ; KONG XIANQI ; GORINE BORIS</creatorcontrib><description>Therapeutic compounds and methods for modulating amyloid deposition in a subject, whatever its clinical setting, are described. Amyloid deposition is modulated by the administration to a subject of an effective amount of a therapeutic compound comprising a phosphonate group and a carboxylate group, a congener thereof, or a pharmaceutically acceptable salt or ester thereof. In preferred embodiments, an interaction between an amyloidogenic protein and a basement membrane constituent is modulated.</description><edition>7</edition><language>eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2001</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20011004&DB=EPODOC&CC=US&NR=2001027186A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20011004&DB=EPODOC&CC=US&NR=2001027186A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>THATCHER GREGORY R.J</creatorcontrib><creatorcontrib>SZAREK WALTER A</creatorcontrib><creatorcontrib>KONG XIANQI</creatorcontrib><creatorcontrib>GORINE BORIS</creatorcontrib><title>Phosphono-carboxylate compounds for treating amyloidosis</title><description>Therapeutic compounds and methods for modulating amyloid deposition in a subject, whatever its clinical setting, are described. Amyloid deposition is modulated by the administration to a subject of an effective amount of a therapeutic compound comprising a phosphonate group and a carboxylate group, a congener thereof, or a pharmaceutically acceptable salt or ester thereof. In preferred embodiments, an interaction between an amyloidogenic protein and a basement membrane constituent is modulated.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2001</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLAIyMgvLsjIz8vXTU4sSsqvqMxJLElVSM7PLcgvzUspVkjLL1IoKUpNLMnMS1dIzK3Myc9MyS_OLOZhYE1LzClO5YXS3AzKbq4hzh66qQX58anFBYnJqXmpJfGhwUYGBoYGRuaGFmaOhsbEqQIAPzEwPA</recordid><startdate>20011004</startdate><enddate>20011004</enddate><creator>THATCHER GREGORY R.J</creator><creator>SZAREK WALTER A</creator><creator>KONG XIANQI</creator><creator>GORINE BORIS</creator><scope>EVB</scope></search><sort><creationdate>20011004</creationdate><title>Phosphono-carboxylate compounds for treating amyloidosis</title><author>THATCHER GREGORY R.J ; SZAREK WALTER A ; KONG XIANQI ; GORINE BORIS</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US2001027186A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2001</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>THATCHER GREGORY R.J</creatorcontrib><creatorcontrib>SZAREK WALTER A</creatorcontrib><creatorcontrib>KONG XIANQI</creatorcontrib><creatorcontrib>GORINE BORIS</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>THATCHER GREGORY R.J</au><au>SZAREK WALTER A</au><au>KONG XIANQI</au><au>GORINE BORIS</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Phosphono-carboxylate compounds for treating amyloidosis</title><date>2001-10-04</date><risdate>2001</risdate><abstract>Therapeutic compounds and methods for modulating amyloid deposition in a subject, whatever its clinical setting, are described. Amyloid deposition is modulated by the administration to a subject of an effective amount of a therapeutic compound comprising a phosphonate group and a carboxylate group, a congener thereof, or a pharmaceutically acceptable salt or ester thereof. In preferred embodiments, an interaction between an amyloidogenic protein and a basement membrane constituent is modulated.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record>
fulltext	fulltext_linktorsrc
identifier
ispartof
issn
language	eng
recordid	cdi_epo_espacenet_US2001027186A1
source	esp@cenet
subjects	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title	Phosphono-carboxylate compounds for treating amyloidosis
url	https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-29T19%3A33%3A28IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=THATCHER%20GREGORY%20R.J&rft.date=2001-10-04&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS2001027186A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true