Proteins binding NKG2D, CD16 and CLEC12A

Described herein are multispecific binding proteins that bind NKG2D receptor, CD16, and CLEC12A, pharmaceutical compositions comprising the multispecific binding proteins, and therapeutic methods useful for the treatment of cancer.

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Hauptverfasser: Chang, Gregory P, Grinberg, Asya, Fallon, Daniel, Baruah, Hemanta, Morgan, Christopher Ryan, Cheung, Ann F, Juo, Zong Sean
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creator Chang, Gregory P
Grinberg, Asya
Fallon, Daniel
Baruah, Hemanta
Morgan, Christopher Ryan
Cheung, Ann F
Juo, Zong Sean
description Described herein are multispecific binding proteins that bind NKG2D receptor, CD16, and CLEC12A, pharmaceutical compositions comprising the multispecific binding proteins, and therapeutic methods useful for the treatment of cancer.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Proteins binding NKG2D, CD16 and CLEC12A
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