Massively parallel processing database for sequence and graph data structures applied to rapid-response drug repurposing

Massively parallel processing database for sequence and graph data structures applied to rapid-response drug repurposing

Systems and methods disclosed herein may include a parallel-processing graph-database solution for protein-sequence analytics to determine a viable therapeutic for a given condition, and may include: determining a protein sequence for the given condition; using sequence database to compare a query s...

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Hauptverfasser: Rickett, Christopher Douglas, Maschhoff, Kristyn J, Sukumar, Sreenivas Rangan
Format: Patent
Sprache:eng
Schlagworte:
CALCULATING
COMPUTING
COUNTING
ELECTRIC DIGITAL DATA PROCESSING
INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS
PHYSICS
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creator Rickett, Christopher Douglas
Maschhoff, Kristyn J
Sukumar, Sreenivas Rangan
description Systems and methods disclosed herein may include a parallel-processing graph-database solution for protein-sequence analytics to determine a viable therapeutic for a given condition, and may include: determining a protein sequence for the given condition; using sequence database to compare a query sequence of the sequence of the given condition with sequences of other known proteins in the sequence database using the sequence database to determine a similarity of the query sequence with sequences of the other known proteins in the sequence database based on the comparison; and querying a graph database based on the similarity of sequences to identify potential therapeutics that could be have an inhibitory effect on the given condition.
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subjects CALCULATING
COMPUTING
COUNTING
ELECTRIC DIGITAL DATA PROCESSING
INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS
PHYSICS
title Massively parallel processing database for sequence and graph data structures applied to rapid-response drug repurposing
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