Fused pyridone compound, and preparation method therefor and use thereof

Disclosed in the present invention are a fused pyridone compound, and a preparation method therefor and a use thereof. Specifically, the present invention discloses a compound of formula (I-B), an optical isomer thereof and a pharmaceutically acceptable salt thereof, and the use of the compound as a...

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Hauptverfasser: Fan, Jun, Guo, Shuchun, Guo, Haibing, Liu, Yang, Bao, Fang, Peng, Jianbiao
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creator Fan, Jun
Guo, Shuchun
Guo, Haibing
Liu, Yang
Bao, Fang
Peng, Jianbiao
description Disclosed in the present invention are a fused pyridone compound, and a preparation method therefor and a use thereof. Specifically, the present invention discloses a compound of formula (I-B), an optical isomer thereof and a pharmaceutically acceptable salt thereof, and the use of the compound as a KRAS inhibitor.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Fused pyridone compound, and preparation method therefor and use thereof
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