Sulfonamide or sulfinamide compound having effect of inducing BRD4 protein degradation and pharmaceutical use thereof

Provided is a compound or a pharmaceutically acceptable salt thereof which is superior in an action inducing degradation of BRD4 protein and useful as a therapeutic agent for cancer. A compound represented by the following formula (I) or a pharmaceutically acceptable salt thereof:wherein each symbol...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Ohba, Kiyomi, Matsudaira, Tetsuji, Niwa, Yasuki, Ibuki, Tatsuya, Hamada, Maiko, Yamazaki, Ryuta
Format: Patent
Sprache:eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator Ohba, Kiyomi
Matsudaira, Tetsuji
Niwa, Yasuki
Ibuki, Tatsuya
Hamada, Maiko
Yamazaki, Ryuta
description Provided is a compound or a pharmaceutically acceptable salt thereof which is superior in an action inducing degradation of BRD4 protein and useful as a therapeutic agent for cancer. A compound represented by the following formula (I) or a pharmaceutically acceptable salt thereof:wherein each symbol is as defined in the DESCRIPTION.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US12102641B2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US12102641B2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US12102641B23</originalsourceid><addsrcrecordid>eNqNi0sKwkAQBbNxIeod2gMIJgYPED-4NroOzUxP0pB0D_Px_EbIAVw96lG1LnKbR6eCE1sCDRBn5AWNTl6zWBjww9IDOUcmgTpgsdn8ruZ5rcEHTcQClvqAFhOrAM6ZHzBMaCgnNjhCjgRpoEDqtsXK4Rhpt-ym2N9vr8vjQF47in6OhFL3bsuqPFbnumyq0z_OF-HcRU8</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Sulfonamide or sulfinamide compound having effect of inducing BRD4 protein degradation and pharmaceutical use thereof</title><source>esp@cenet</source><creator>Ohba, Kiyomi ; Matsudaira, Tetsuji ; Niwa, Yasuki ; Ibuki, Tatsuya ; Hamada, Maiko ; Yamazaki, Ryuta</creator><creatorcontrib>Ohba, Kiyomi ; Matsudaira, Tetsuji ; Niwa, Yasuki ; Ibuki, Tatsuya ; Hamada, Maiko ; Yamazaki, Ryuta</creatorcontrib><description>Provided is a compound or a pharmaceutically acceptable salt thereof which is superior in an action inducing degradation of BRD4 protein and useful as a therapeutic agent for cancer. A compound represented by the following formula (I) or a pharmaceutically acceptable salt thereof:wherein each symbol is as defined in the DESCRIPTION.</description><language>eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20241001&amp;DB=EPODOC&amp;CC=US&amp;NR=12102641B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76318</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20241001&amp;DB=EPODOC&amp;CC=US&amp;NR=12102641B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Ohba, Kiyomi</creatorcontrib><creatorcontrib>Matsudaira, Tetsuji</creatorcontrib><creatorcontrib>Niwa, Yasuki</creatorcontrib><creatorcontrib>Ibuki, Tatsuya</creatorcontrib><creatorcontrib>Hamada, Maiko</creatorcontrib><creatorcontrib>Yamazaki, Ryuta</creatorcontrib><title>Sulfonamide or sulfinamide compound having effect of inducing BRD4 protein degradation and pharmaceutical use thereof</title><description>Provided is a compound or a pharmaceutically acceptable salt thereof which is superior in an action inducing degradation of BRD4 protein and useful as a therapeutic agent for cancer. A compound represented by the following formula (I) or a pharmaceutically acceptable salt thereof:wherein each symbol is as defined in the DESCRIPTION.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNi0sKwkAQBbNxIeod2gMIJgYPED-4NroOzUxP0pB0D_Px_EbIAVw96lG1LnKbR6eCE1sCDRBn5AWNTl6zWBjww9IDOUcmgTpgsdn8ruZ5rcEHTcQClvqAFhOrAM6ZHzBMaCgnNjhCjgRpoEDqtsXK4Rhpt-ym2N9vr8vjQF47in6OhFL3bsuqPFbnumyq0z_OF-HcRU8</recordid><startdate>20241001</startdate><enddate>20241001</enddate><creator>Ohba, Kiyomi</creator><creator>Matsudaira, Tetsuji</creator><creator>Niwa, Yasuki</creator><creator>Ibuki, Tatsuya</creator><creator>Hamada, Maiko</creator><creator>Yamazaki, Ryuta</creator><scope>EVB</scope></search><sort><creationdate>20241001</creationdate><title>Sulfonamide or sulfinamide compound having effect of inducing BRD4 protein degradation and pharmaceutical use thereof</title><author>Ohba, Kiyomi ; Matsudaira, Tetsuji ; Niwa, Yasuki ; Ibuki, Tatsuya ; Hamada, Maiko ; Yamazaki, Ryuta</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US12102641B23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2024</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>Ohba, Kiyomi</creatorcontrib><creatorcontrib>Matsudaira, Tetsuji</creatorcontrib><creatorcontrib>Niwa, Yasuki</creatorcontrib><creatorcontrib>Ibuki, Tatsuya</creatorcontrib><creatorcontrib>Hamada, Maiko</creatorcontrib><creatorcontrib>Yamazaki, Ryuta</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Ohba, Kiyomi</au><au>Matsudaira, Tetsuji</au><au>Niwa, Yasuki</au><au>Ibuki, Tatsuya</au><au>Hamada, Maiko</au><au>Yamazaki, Ryuta</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Sulfonamide or sulfinamide compound having effect of inducing BRD4 protein degradation and pharmaceutical use thereof</title><date>2024-10-01</date><risdate>2024</risdate><abstract>Provided is a compound or a pharmaceutically acceptable salt thereof which is superior in an action inducing degradation of BRD4 protein and useful as a therapeutic agent for cancer. A compound represented by the following formula (I) or a pharmaceutically acceptable salt thereof:wherein each symbol is as defined in the DESCRIPTION.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_epo_espacenet_US12102641B2
source esp@cenet
subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Sulfonamide or sulfinamide compound having effect of inducing BRD4 protein degradation and pharmaceutical use thereof
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-11T04%3A40%3A39IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Ohba,%20Kiyomi&rft.date=2024-10-01&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS12102641B2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true