Methods and compositions for theranostic nanoparticles

Provided herein is a nanoparticle for drug delivery, wherein the nanoparticle comprises a hyperbranched polyester (HBPE) nanoparticle having a hydrophobic interior, polyglutamate folate ligands conjugated to the nanoparticle, and one or more PET detectable isotopes. Also provided herein are methods...

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Hauptverfasser: Grimm, Jan, Santra, Santimukul, Sessions, Hampton, Perez Figueroa, Jesus Manuel, Khaled, Annette, Kaittanis, Charalambos, Santiesteban, Oscar
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creator Grimm, Jan
Santra, Santimukul
Sessions, Hampton
Perez Figueroa, Jesus Manuel
Khaled, Annette
Kaittanis, Charalambos
Santiesteban, Oscar
description Provided herein is a nanoparticle for drug delivery, wherein the nanoparticle comprises a hyperbranched polyester (HBPE) nanoparticle having a hydrophobic interior, polyglutamate folate ligands conjugated to the nanoparticle, and one or more PET detectable isotopes. Also provided herein are methods of using thereof.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Methods and compositions for theranostic nanoparticles
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