Antibodies against ILT2 and use thereof

The present disclosure provides monoclonal anti-ILT2 antibodies or antigen-binding fragments thereof, as well as pharmaceutical compositions comprising the same and methods of producing the same. Also provided are methods of treating cancer using the antibodies or compositions of the present disclos...

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Hauptverfasser: Haves Ziv, Dana, Ben-Moshe, Tehila, Sapir, Yair, Hakim, Motti, Shulman, Avidor, Goldshtein, Ilana, Alishekevitz, Dror, Fridman-Dror, Anna, Mandel, Ilana, Peretz, Tsuri
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creator Haves Ziv, Dana
Ben-Moshe, Tehila
Sapir, Yair
Hakim, Motti
Shulman, Avidor
Goldshtein, Ilana
Alishekevitz, Dror
Fridman-Dror, Anna
Mandel, Ilana
Peretz, Tsuri
description The present disclosure provides monoclonal anti-ILT2 antibodies or antigen-binding fragments thereof, as well as pharmaceutical compositions comprising the same and methods of producing the same. Also provided are methods of treating cancer using the antibodies or compositions of the present disclosure. Methods of patient selection are also provided.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
TESTING
title Antibodies against ILT2 and use thereof
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