Treating sickle cell disease with a pyruvate kinase R activating compound
Compounds that activate pyruvate kinase R can be used for the treatment of sickle cell disease (SCD). Methods and compositions for the treatment of SCD are provided herein, including a therapeutic compound designated as Compound 1.
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| creator | Gustafson, Gary Han, Bingsong Smith, Chase C Mitchell, Lorna Richard, David Lancia, Jr., David R Ericsson, Anna Green, Neal Wang, Zhongguo Shelekhin, Tatiana Zheng, Xiaozhang |
| description | Compounds that activate pyruvate kinase R can be used for the treatment of sickle cell disease (SCD). Methods and compositions for the treatment of SCD are provided herein, including a therapeutic compound designated as Compound 1. |
| format | Patent |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Treating sickle cell disease with a pyruvate kinase R activating compound |
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