Anti-O1 antibodies and uses thereof

The present disclosure provides binding proteins (e.g., antibodies or antigen binding fragments thereof) that specifically bind to Klebsiella pneumoniae O1 and induce opsonophagocytic killing of Klebsiella (e.g., Klebsiella pneumoniae). The present disclosure also provides methods of reducing Klebsi...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Chang, Chew-shun, Cameroni, Elisabetta, Beltramello, Martina, Wang, Qun, Stover, Charles K, Xiao, Xiaodong, Pennini, Meghan, Hilliard, Jamese, Kaplan, Gilad, Corti, Davide
Format: Patent
Sprache:eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator Chang, Chew-shun
Cameroni, Elisabetta
Beltramello, Martina
Wang, Qun
Stover, Charles K
Xiao, Xiaodong
Pennini, Meghan
Hilliard, Jamese
Kaplan, Gilad
Corti, Davide
description The present disclosure provides binding proteins (e.g., antibodies or antigen binding fragments thereof) that specifically bind to Klebsiella pneumoniae O1 and induce opsonophagocytic killing of Klebsiella (e.g., Klebsiella pneumoniae). The present disclosure also provides methods of reducing Klebsiella (e.g., Klebsiella pneumoniae) or treating or preventing Klebsiella (e.g., Klebsiella pneumoniae) infection in a subject comprising administering the Klebsiella pneumoniae O1 binding proteins, (e.g., antibodies or antigen-binding fragments thereof) to the subject.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US12018068B2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US12018068B2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US12018068B23</originalsourceid><addsrcrecordid>eNrjZFB2zCvJ1PU3VEgE0kn5KZmpxUBmikJpMZBRkpFalJqfxsPAmpaYU5zKC6W5GRTdXEOcPXRTC_LjU4sLEpNT81JL4kODDY0MDC0MzCycjIyJUQMAm5wl7Q</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Anti-O1 antibodies and uses thereof</title><source>esp@cenet</source><creator>Chang, Chew-shun ; Cameroni, Elisabetta ; Beltramello, Martina ; Wang, Qun ; Stover, Charles K ; Xiao, Xiaodong ; Pennini, Meghan ; Hilliard, Jamese ; Kaplan, Gilad ; Corti, Davide</creator><creatorcontrib>Chang, Chew-shun ; Cameroni, Elisabetta ; Beltramello, Martina ; Wang, Qun ; Stover, Charles K ; Xiao, Xiaodong ; Pennini, Meghan ; Hilliard, Jamese ; Kaplan, Gilad ; Corti, Davide</creatorcontrib><description>The present disclosure provides binding proteins (e.g., antibodies or antigen binding fragments thereof) that specifically bind to Klebsiella pneumoniae O1 and induce opsonophagocytic killing of Klebsiella (e.g., Klebsiella pneumoniae). The present disclosure also provides methods of reducing Klebsiella (e.g., Klebsiella pneumoniae) or treating or preventing Klebsiella (e.g., Klebsiella pneumoniae) infection in a subject comprising administering the Klebsiella pneumoniae O1 binding proteins, (e.g., antibodies or antigen-binding fragments thereof) to the subject.</description><language>eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20240625&amp;DB=EPODOC&amp;CC=US&amp;NR=12018068B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20240625&amp;DB=EPODOC&amp;CC=US&amp;NR=12018068B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Chang, Chew-shun</creatorcontrib><creatorcontrib>Cameroni, Elisabetta</creatorcontrib><creatorcontrib>Beltramello, Martina</creatorcontrib><creatorcontrib>Wang, Qun</creatorcontrib><creatorcontrib>Stover, Charles K</creatorcontrib><creatorcontrib>Xiao, Xiaodong</creatorcontrib><creatorcontrib>Pennini, Meghan</creatorcontrib><creatorcontrib>Hilliard, Jamese</creatorcontrib><creatorcontrib>Kaplan, Gilad</creatorcontrib><creatorcontrib>Corti, Davide</creatorcontrib><title>Anti-O1 antibodies and uses thereof</title><description>The present disclosure provides binding proteins (e.g., antibodies or antigen binding fragments thereof) that specifically bind to Klebsiella pneumoniae O1 and induce opsonophagocytic killing of Klebsiella (e.g., Klebsiella pneumoniae). The present disclosure also provides methods of reducing Klebsiella (e.g., Klebsiella pneumoniae) or treating or preventing Klebsiella (e.g., Klebsiella pneumoniae) infection in a subject comprising administering the Klebsiella pneumoniae O1 binding proteins, (e.g., antibodies or antigen-binding fragments thereof) to the subject.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFB2zCvJ1PU3VEgE0kn5KZmpxUBmikJpMZBRkpFalJqfxsPAmpaYU5zKC6W5GRTdXEOcPXRTC_LjU4sLEpNT81JL4kODDY0MDC0MzCycjIyJUQMAm5wl7Q</recordid><startdate>20240625</startdate><enddate>20240625</enddate><creator>Chang, Chew-shun</creator><creator>Cameroni, Elisabetta</creator><creator>Beltramello, Martina</creator><creator>Wang, Qun</creator><creator>Stover, Charles K</creator><creator>Xiao, Xiaodong</creator><creator>Pennini, Meghan</creator><creator>Hilliard, Jamese</creator><creator>Kaplan, Gilad</creator><creator>Corti, Davide</creator><scope>EVB</scope></search><sort><creationdate>20240625</creationdate><title>Anti-O1 antibodies and uses thereof</title><author>Chang, Chew-shun ; Cameroni, Elisabetta ; Beltramello, Martina ; Wang, Qun ; Stover, Charles K ; Xiao, Xiaodong ; Pennini, Meghan ; Hilliard, Jamese ; Kaplan, Gilad ; Corti, Davide</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US12018068B23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2024</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>Chang, Chew-shun</creatorcontrib><creatorcontrib>Cameroni, Elisabetta</creatorcontrib><creatorcontrib>Beltramello, Martina</creatorcontrib><creatorcontrib>Wang, Qun</creatorcontrib><creatorcontrib>Stover, Charles K</creatorcontrib><creatorcontrib>Xiao, Xiaodong</creatorcontrib><creatorcontrib>Pennini, Meghan</creatorcontrib><creatorcontrib>Hilliard, Jamese</creatorcontrib><creatorcontrib>Kaplan, Gilad</creatorcontrib><creatorcontrib>Corti, Davide</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Chang, Chew-shun</au><au>Cameroni, Elisabetta</au><au>Beltramello, Martina</au><au>Wang, Qun</au><au>Stover, Charles K</au><au>Xiao, Xiaodong</au><au>Pennini, Meghan</au><au>Hilliard, Jamese</au><au>Kaplan, Gilad</au><au>Corti, Davide</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Anti-O1 antibodies and uses thereof</title><date>2024-06-25</date><risdate>2024</risdate><abstract>The present disclosure provides binding proteins (e.g., antibodies or antigen binding fragments thereof) that specifically bind to Klebsiella pneumoniae O1 and induce opsonophagocytic killing of Klebsiella (e.g., Klebsiella pneumoniae). The present disclosure also provides methods of reducing Klebsiella (e.g., Klebsiella pneumoniae) or treating or preventing Klebsiella (e.g., Klebsiella pneumoniae) infection in a subject comprising administering the Klebsiella pneumoniae O1 binding proteins, (e.g., antibodies or antigen-binding fragments thereof) to the subject.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_epo_espacenet_US12018068B2
source esp@cenet
subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title Anti-O1 antibodies and uses thereof
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-23T04%3A07%3A43IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Chang,%20Chew-shun&rft.date=2024-06-25&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS12018068B2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true