FimH mutant, compositions therewith and use thereof

Polypeptides comprising a FimH lectin domain comprising an amino acid mutation that causes the FimH lectin domain to be in the low affinity conformation for mannose are described. Pharmaceutical compositions which comprise such polypeptides and methods of stimulating an immune response in a subject...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	Grijpstra, Jan, Geurtsen, Jeroen, Feitsma, Jakob Louris, Weerdenburg, Marleen Eveline, Fae, Cristhina Kellen
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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