N-azaspirocycloalkane substituted N-heteroaryl compounds and compositions for inhibiting the activity of SHP2

The present invention relates to compounds of formula I:in which p, q, Y1, Y2, R1, R2a, R2b, R3a, R3b, R4a, R4b, R5a, R5b, R7 and R8 are defined in the Summary of the Invention; capable of inhibiting the activity of SHP2. The invention further provides a process for the preparation of compounds of t...

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Bibliographische Detailangaben

Hauptverfasser:	Giraldes, John William, Toure, Bakary-Barry, Chen, Christine Hiu-Tung, Chen, Zhuoliang, Sendzik, Martin, Kato, Mitsunori, Williams, Sarah, Karki, Rajesh, Dore, Michael, LaMarche, Matthew J, Smith, Troy Douglas, Perez, Lawrence Blas, Fortanet, Jorge Garcia
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
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