Compounds and methods useful for stabilizing phenylalanine hydroxylase mutations

The disclosure relates to compounds of Formula I or a pharmaceutically acceptable salt thereof, wherein, m, R1-R5, R5A, and L are defined herein.These compounds are useful in methods for stabilizing a mutant PAH protein or reducing blood phenylalanine concentration in a subject suffering from phenyl...

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Bibliographische Detailangaben
Hauptverfasser: Konteatis, Zenon D, De Pascalis, Lucrezia, King, Sandra, Shook, Brian C, Finlay, Heather Jane
Format: Patent
Sprache:eng
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