Stable, concentrated radionuclide complex solutions
The present invention relates to radionuclide complex solutions of high concentration and of high chemical stability, that allows their use as drug product for diagnostic and/or therapeutic purposes. The stability of the drug product is achieved by at least one stabilizer against radiolytic degradat...
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| creator | de Palo, Francesco Brambati, Clementina Tesoriere, Giovanni Fugazza, Lorenza Chicco, Daniela Barbato, Donato Mariani, Maurizio |
| description | The present invention relates to radionuclide complex solutions of high concentration and of high chemical stability, that allows their use as drug product for diagnostic and/or therapeutic purposes. The stability of the drug product is achieved by at least one stabilizer against radiolytic degradation. The use of two stabilizers introduced during the manufacturing process at different stages was found to be of particular advantage. |
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| subjects | CHEMISTRY DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY FERROUS OR NON-FERROUS ALLOYS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRETREATMENT OF RAW MATERIALS PRODUCTION AND REFINING OF METALS TREATMENT OF ALLOYS OR NON-FERROUS METALS |
| title | Stable, concentrated radionuclide complex solutions |
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