Aryl piperidines as monoacylglycerol lipase modulators
Aryl piperidine compounds of Formula (I), and pharmaceutically acceptable salts, isotopes, N-oxides, solvates, and stereoisomers thereof, pharmaceutical compositions containing them, and methods of using them including methods for treating disease states, disorders, and conditions associated with MG...
Gespeichert in:
| Hauptverfasser: | , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | Wade, Warren S Garcia-Reynaga, Pablo Ameriks, Michael K Samant, Andrew V Berry, Cynthia B Biró, Krisztián |
| description | Aryl piperidine compounds of Formula (I), and pharmaceutically acceptable salts, isotopes, N-oxides, solvates, and stereoisomers thereof, pharmaceutical compositions containing them, and methods of using them including methods for treating disease states, disorders, and conditions associated with MGL modulation, such as those associated with pain, psychiatric disorders, neurological disorders (including, but not limited to major depressive disorder, treatment resistant depression, anxious depression, autism spectrum disorders, Asperger syndrome, bipolar disorder), cancers and eye conditions:wherein X, R2a, R2b, R3, R4, R5a and R5b are as defined herein. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US11787798B2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US11787798B2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US11787798B23</originalsourceid><addsrcrecordid>eNrjZDBzLKrMUSjILEgtykzJzEstVkgsVsjNz8tPTK7MSc-pTE4tys9RyMksSCxOBYqnlOYkluQXFfMwsKYl5hSn8kJpbgZFN9cQZw_d1IL8-NTigsTk1LzUkvjQYENDcwtzc0sLJyNjYtQAAPhXLqQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Aryl piperidines as monoacylglycerol lipase modulators</title><source>esp@cenet</source><creator>Wade, Warren S ; Garcia-Reynaga, Pablo ; Ameriks, Michael K ; Samant, Andrew V ; Berry, Cynthia B ; Biró, Krisztián</creator><creatorcontrib>Wade, Warren S ; Garcia-Reynaga, Pablo ; Ameriks, Michael K ; Samant, Andrew V ; Berry, Cynthia B ; Biró, Krisztián</creatorcontrib><description>Aryl piperidine compounds of Formula (I), and pharmaceutically acceptable salts, isotopes, N-oxides, solvates, and stereoisomers thereof, pharmaceutical compositions containing them, and methods of using them including methods for treating disease states, disorders, and conditions associated with MGL modulation, such as those associated with pain, psychiatric disorders, neurological disorders (including, but not limited to major depressive disorder, treatment resistant depression, anxious depression, autism spectrum disorders, Asperger syndrome, bipolar disorder), cancers and eye conditions:wherein X, R2a, R2b, R3, R4, R5a and R5b are as defined herein.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20231017&DB=EPODOC&CC=US&NR=11787798B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20231017&DB=EPODOC&CC=US&NR=11787798B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Wade, Warren S</creatorcontrib><creatorcontrib>Garcia-Reynaga, Pablo</creatorcontrib><creatorcontrib>Ameriks, Michael K</creatorcontrib><creatorcontrib>Samant, Andrew V</creatorcontrib><creatorcontrib>Berry, Cynthia B</creatorcontrib><creatorcontrib>Biró, Krisztián</creatorcontrib><title>Aryl piperidines as monoacylglycerol lipase modulators</title><description>Aryl piperidine compounds of Formula (I), and pharmaceutically acceptable salts, isotopes, N-oxides, solvates, and stereoisomers thereof, pharmaceutical compositions containing them, and methods of using them including methods for treating disease states, disorders, and conditions associated with MGL modulation, such as those associated with pain, psychiatric disorders, neurological disorders (including, but not limited to major depressive disorder, treatment resistant depression, anxious depression, autism spectrum disorders, Asperger syndrome, bipolar disorder), cancers and eye conditions:wherein X, R2a, R2b, R3, R4, R5a and R5b are as defined herein.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDBzLKrMUSjILEgtykzJzEstVkgsVsjNz8tPTK7MSc-pTE4tys9RyMksSCxOBYqnlOYkluQXFfMwsKYl5hSn8kJpbgZFN9cQZw_d1IL8-NTigsTk1LzUkvjQYENDcwtzc0sLJyNjYtQAAPhXLqQ</recordid><startdate>20231017</startdate><enddate>20231017</enddate><creator>Wade, Warren S</creator><creator>Garcia-Reynaga, Pablo</creator><creator>Ameriks, Michael K</creator><creator>Samant, Andrew V</creator><creator>Berry, Cynthia B</creator><creator>Biró, Krisztián</creator><scope>EVB</scope></search><sort><creationdate>20231017</creationdate><title>Aryl piperidines as monoacylglycerol lipase modulators</title><author>Wade, Warren S ; Garcia-Reynaga, Pablo ; Ameriks, Michael K ; Samant, Andrew V ; Berry, Cynthia B ; Biró, Krisztián</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US11787798B23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2023</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>Wade, Warren S</creatorcontrib><creatorcontrib>Garcia-Reynaga, Pablo</creatorcontrib><creatorcontrib>Ameriks, Michael K</creatorcontrib><creatorcontrib>Samant, Andrew V</creatorcontrib><creatorcontrib>Berry, Cynthia B</creatorcontrib><creatorcontrib>Biró, Krisztián</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Wade, Warren S</au><au>Garcia-Reynaga, Pablo</au><au>Ameriks, Michael K</au><au>Samant, Andrew V</au><au>Berry, Cynthia B</au><au>Biró, Krisztián</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Aryl piperidines as monoacylglycerol lipase modulators</title><date>2023-10-17</date><risdate>2023</risdate><abstract>Aryl piperidine compounds of Formula (I), and pharmaceutically acceptable salts, isotopes, N-oxides, solvates, and stereoisomers thereof, pharmaceutical compositions containing them, and methods of using them including methods for treating disease states, disorders, and conditions associated with MGL modulation, such as those associated with pain, psychiatric disorders, neurological disorders (including, but not limited to major depressive disorder, treatment resistant depression, anxious depression, autism spectrum disorders, Asperger syndrome, bipolar disorder), cancers and eye conditions:wherein X, R2a, R2b, R3, R4, R5a and R5b are as defined herein.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_epo_espacenet_US11787798B2 |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY |
| title | Aryl piperidines as monoacylglycerol lipase modulators |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-04T13%3A10%3A42IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Wade,%20Warren%20S&rft.date=2023-10-17&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS11787798B2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |