Pyrazolo[3,4-b]pyridine compounds as inhibitors of TAM and MET kinases

Pyrazolo[3,4-b]pyridine compounds as inhibitors of TAM and MET kinases

Provided herein are compounds of the Formula (I): and stereoisomers, tautomers and pharmaceutically acceptable salts thereof, wherein R1, R2, R9, X1 and G are as defined herein, which are inhibitors of one or more TAM kinases and/or c-Met kinase, and are useful in the treatment and prevention of dis...

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Bibliographische Detailangaben
Hauptverfasser: Barbour, Patrick, Dahlke, Joshua, Zhao, Qian, Allen, Shelley, McNulty, Oren T, Cook, Adam, Laird, Ellen, Hinklin, Ronald Jay, Gaudino, John
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:Provided herein are compounds of the Formula (I): and stereoisomers, tautomers and pharmaceutically acceptable salts thereof, wherein R1, R2, R9, X1 and G are as defined herein, which are inhibitors of one or more TAM kinases and/or c-Met kinase, and are useful in the treatment and prevention of diseases which can be treated with a TAM kinase inhibitor and/or a c-Met kinase inhibitor.