Anti-bacterial compositions comparing lytic modified bacteriophage engineered to infect and kill different target bacteria

A modified bacteriophage capable of infecting a plurality of different target bacteria, which bacteriophage includes a toxin gene encoding a toxin protein which is toxic to the target bacteria; wherein the bacteriophage is lytic; and wherein the bacteriophage expresses host range determinant protein...

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Bibliographische Detailangaben
Hauptverfasser: Fairhead, Heather, Wilkinson, Adam
Format: Patent
Sprache:eng
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Zusammenfassung:A modified bacteriophage capable of infecting a plurality of different target bacteria, which bacteriophage includes a toxin gene encoding a toxin protein which is toxic to the target bacteria; wherein the bacteriophage is lytic; and wherein the bacteriophage expresses host range determinant proteins which have a plurality of bacterial host specificities.