Imidazopyridazines as modulators of IL-17

Imidazopyridazines as modulators of IL-17

The present application discloses compounds having the following formula:or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4 and R5 are defined in the specification, as well as methods of making and using the compounds disclosed herein for treating or ameliorating an IL-17 mediated...

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Hauptverfasser: Rovira, Alexander Raymond, Goldberg, Steven, Meduna, Steven P, McCarver, Stefan, Valdes, Alexander, Loskot, Steven, Xue, Xiaohua, Behenna, Douglas, Woods, Craig, Rhorer, Timothy B, Martin, Connor
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CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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creator Rovira, Alexander Raymond
Goldberg, Steven
Meduna, Steven P
McCarver, Stefan
Valdes, Alexander
Loskot, Steven
Xue, Xiaohua
Behenna, Douglas
Woods, Craig
Rhorer, Timothy B
Martin, Connor
description The present application discloses compounds having the following formula:or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4 and R5 are defined in the specification, as well as methods of making and using the compounds disclosed herein for treating or ameliorating an IL-17 mediated syndrome, disorder and/or disease.
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HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title Imidazopyridazines as modulators of IL-17
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