Histone deacetylase inhibitors for immunomodulation in tumor microenvironment

The present disclosure generally relates to compounds class I HDAC inhibitors, their production and applications. The compounds possess epigenetic immunomodulatory activities in the tumor microenvironment (TME) and thus inhibit growth of tumor cells.

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	Chu, Sz-Hao, Chou, Cheng-Han, Chao, Ye-Su, Chen, Jia-Shiong, Wu, Yi-Hong, Yang, Mu-Hsuan, Chen, Chia-Nan
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

container_end_page
container_issue
container_start_page
container_title
container_volume
creator	Chu, Sz-Hao Chou, Cheng-Han Chao, Ye-Su Chen, Jia-Shiong Wu, Yi-Hong Yang, Mu-Hsuan Chen, Chia-Nan
description	The present disclosure generally relates to compounds class I HDAC inhibitors, their production and applications. The compounds possess epigenetic immunomodulatory activities in the tumor microenvironment (TME) and thus inhibit growth of tumor cells.
format	Patent
fullrecord	<record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US11672788B2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US11672788B2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US11672788B23</originalsourceid><addsrcrecordid>eNqNjTEOwjAMALMwIOAP4QEMLRLtDAJ1YQLmKrSusBTbVewg8Xsy8ACmG-6kW7prh2rC4EcIA9gnBgWP_MInmiT1kySPRJmFZMwxGAoX7y1TMYRDEuA3JmECtrVbTCEqbH5cue3lfD91O5ilB53LgsH6x62qDk3dtO2x3v_TfAGNgDfm</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Histone deacetylase inhibitors for immunomodulation in tumor microenvironment</title><source>esp@cenet</source><creator>Chu, Sz-Hao ; Chou, Cheng-Han ; Chao, Ye-Su ; Chen, Jia-Shiong ; Wu, Yi-Hong ; Yang, Mu-Hsuan ; Chen, Chia-Nan</creator><creatorcontrib>Chu, Sz-Hao ; Chou, Cheng-Han ; Chao, Ye-Su ; Chen, Jia-Shiong ; Wu, Yi-Hong ; Yang, Mu-Hsuan ; Chen, Chia-Nan</creatorcontrib><description>The present disclosure generally relates to compounds class I HDAC inhibitors, their production and applications. The compounds possess epigenetic immunomodulatory activities in the tumor microenvironment (TME) and thus inhibit growth of tumor cells.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230613&DB=EPODOC&CC=US&NR=11672788B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25569,76552</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230613&DB=EPODOC&CC=US&NR=11672788B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Chu, Sz-Hao</creatorcontrib><creatorcontrib>Chou, Cheng-Han</creatorcontrib><creatorcontrib>Chao, Ye-Su</creatorcontrib><creatorcontrib>Chen, Jia-Shiong</creatorcontrib><creatorcontrib>Wu, Yi-Hong</creatorcontrib><creatorcontrib>Yang, Mu-Hsuan</creatorcontrib><creatorcontrib>Chen, Chia-Nan</creatorcontrib><title>Histone deacetylase inhibitors for immunomodulation in tumor microenvironment</title><description>The present disclosure generally relates to compounds class I HDAC inhibitors, their production and applications. The compounds possess epigenetic immunomodulatory activities in the tumor microenvironment (TME) and thus inhibit growth of tumor cells.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjTEOwjAMALMwIOAP4QEMLRLtDAJ1YQLmKrSusBTbVewg8Xsy8ACmG-6kW7prh2rC4EcIA9gnBgWP_MInmiT1kySPRJmFZMwxGAoX7y1TMYRDEuA3JmECtrVbTCEqbH5cue3lfD91O5ilB53LgsH6x62qDk3dtO2x3v_TfAGNgDfm</recordid><startdate>20230613</startdate><enddate>20230613</enddate><creator>Chu, Sz-Hao</creator><creator>Chou, Cheng-Han</creator><creator>Chao, Ye-Su</creator><creator>Chen, Jia-Shiong</creator><creator>Wu, Yi-Hong</creator><creator>Yang, Mu-Hsuan</creator><creator>Chen, Chia-Nan</creator><scope>EVB</scope></search><sort><creationdate>20230613</creationdate><title>Histone deacetylase inhibitors for immunomodulation in tumor microenvironment</title><author>Chu, Sz-Hao ; Chou, Cheng-Han ; Chao, Ye-Su ; Chen, Jia-Shiong ; Wu, Yi-Hong ; Yang, Mu-Hsuan ; Chen, Chia-Nan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US11672788B23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2023</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>Chu, Sz-Hao</creatorcontrib><creatorcontrib>Chou, Cheng-Han</creatorcontrib><creatorcontrib>Chao, Ye-Su</creatorcontrib><creatorcontrib>Chen, Jia-Shiong</creatorcontrib><creatorcontrib>Wu, Yi-Hong</creatorcontrib><creatorcontrib>Yang, Mu-Hsuan</creatorcontrib><creatorcontrib>Chen, Chia-Nan</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Chu, Sz-Hao</au><au>Chou, Cheng-Han</au><au>Chao, Ye-Su</au><au>Chen, Jia-Shiong</au><au>Wu, Yi-Hong</au><au>Yang, Mu-Hsuan</au><au>Chen, Chia-Nan</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Histone deacetylase inhibitors for immunomodulation in tumor microenvironment</title><date>2023-06-13</date><risdate>2023</risdate><abstract>The present disclosure generally relates to compounds class I HDAC inhibitors, their production and applications. The compounds possess epigenetic immunomodulatory activities in the tumor microenvironment (TME) and thus inhibit growth of tumor cells.</abstract><oa>free_for_read</oa></addata></record>
fulltext	fulltext_linktorsrc
identifier
ispartof
issn
language	eng
recordid	cdi_epo_espacenet_US11672788B2
source	esp@cenet
subjects	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title	Histone deacetylase inhibitors for immunomodulation in tumor microenvironment
url	https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-15T08%3A33%3A41IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Chu,%20Sz-Hao&rft.date=2023-06-13&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS11672788B2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true