Allosteric chromenone inhibitors of phosphoinositide 3-kinase (PI3K) for the treatment of disease

The disclosure relates to compounds of Formula (I) as allosteric chromenone inhibitors of phosphoinositide 3-kinase (PI3K) useful in the treatment of diseases or disorders associated with PI3K modulation, Formula (I):or a prodrug, solvate, enantiomer, stereoisomer, tautomer, or pharmaceutically acce...

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Hauptverfasser: Dahlgren, Markus K, Knight, Jennifer Lynn, Kesicki, Edward A, Klippel-Giese, Anke, Mayne, Christopher Glenn, McElligott, David L, Long, Katelyn Frances, Aronow, Sean Douglas, Ravi, Kannan Karukurichi, Feng, Shulu, Widjaja, Tien, Hickey, Eugene R, Kolakowski, Gabrielle R, Severance, Daniel Lee, Irvin, Thomas Combs, Puca, Loredana, Anderson, Erin Danielle, Boyles, Nicholas A, Gerasyuto, Aleksey I, Kumar, Manoj, Welch, Michael Brian, McLean, Johnathan Alexander
Format: Patent
Sprache:eng
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