Data center that regulates air pressure within an interior compartment

A data center provides containment walls of an operation technology (OT) interior compartment, such as a meet me room, positioned between cold and hot aisles in an information technology (IT compartment. The OT interior compartment limits air flow so that IT components outside of the OT interior compartment receive sufficient supply air for moderating or cooling a temperature of the IT components. Pressure differential is measured on an exterior and interior of door(s) to the OT interior compartment. Air flow regulation device(s) are positioned in a supply air passage to the OT interior compartment and/or in a return air passage out of the OT interior compartment are controlled to limit the pressure differential between an exterior and interior of the containment wall. Limiting the pressure differential ensures that door(s) facing the cold aisle are not difficult to open and door(s) facing the hot aisle are not difficult to close.