MASP-2 inhibitors and methods of use

The present disclosure provides, inter alia, compounds with MASP-2 inhibitory activity, compositions of such compounds and methods of making and using such compounds.

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Hauptverfasser: Tsoung, Jennifer, Khalaf, Juhienah, Gruswitz, Franz A, Keshipeddy, Santosh Kumar, Cicirelli, Michael, Kwon, Do Yeon, Vaddela, Sudheer Babu, Nguyen, Jeremiah H, Nollert von Specht, Peter Kurt, Gage, Jennifer Lynn, Cutshall, Neil S, Little, Thomas L, Goldstein, Sara Rebecca, Lemus, Robert Huerta, Metz, Markus
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creator Tsoung, Jennifer
Khalaf, Juhienah
Gruswitz, Franz A
Keshipeddy, Santosh Kumar
Cicirelli, Michael
Kwon, Do Yeon
Vaddela, Sudheer Babu
Nguyen, Jeremiah H
Nollert von Specht, Peter Kurt
Gage, Jennifer Lynn
Cutshall, Neil S
Little, Thomas L
Goldstein, Sara Rebecca
Lemus, Robert Huerta
Metz, Markus
description The present disclosure provides, inter alia, compounds with MASP-2 inhibitory activity, compositions of such compounds and methods of making and using such compounds.
format Patent
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title MASP-2 inhibitors and methods of use
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