Tuning mechanism for OAR and target objectives during optimization
In radiation treatment planning, a plurality of optimization loops are performed. In each optimization loop computes a dose distribution (60) in a patient represented by a planning image (42) with regions of interest (ROIs) defined in the planning image. Weights (64) for objective functions (50) are...
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| creator | Bzdusek, Karl Antonin |
| description | In radiation treatment planning, a plurality of optimization loops are performed. In each optimization loop computes a dose distribution (60) in a patient represented by a planning image (42) with regions of interest (ROIs) defined in the planning image. Weights (64) for objective functions (50) are determined from objective function value (OFV) goals (52) for the objective functions. An optimized dose distribution is produced by adjusting the plan parameters to optimize the computed dose distribution respective to composite objective function (62). At least one optimization loop may include updating (70) at least one OFV goal to be used in at least the next performed optimization loop. At least one optimization loop may include updating an objective function quantifying compliance with a target dose for a target ROI based on a comparison of a metric of coverage of the target ROI and a desired coverage of the target ROI. |
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In each optimization loop computes a dose distribution (60) in a patient represented by a planning image (42) with regions of interest (ROIs) defined in the planning image. Weights (64) for objective functions (50) are determined from objective function value (OFV) goals (52) for the objective functions. An optimized dose distribution is produced by adjusting the plan parameters to optimize the computed dose distribution respective to composite objective function (62). At least one optimization loop may include updating (70) at least one OFV goal to be used in at least the next performed optimization loop. At least one optimization loop may include updating an objective function quantifying compliance with a target dose for a target ROI based on a comparison of a metric of coverage of the target ROI and a desired coverage of the target ROI.</description><language>eng</language><subject>ELECTROTHERAPY ; HUMAN NECESSITIES ; HYGIENE ; MAGNETOTHERAPY ; MEDICAL OR VETERINARY SCIENCE ; RADIATION THERAPY ; ULTRASOUND THERAPY</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20221206&DB=EPODOC&CC=US&NR=11517766B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20221206&DB=EPODOC&CC=US&NR=11517766B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Bzdusek, Karl Antonin</creatorcontrib><title>Tuning mechanism for OAR and target objectives during optimization</title><description>In radiation treatment planning, a plurality of optimization loops are performed. 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| subjects | ELECTROTHERAPY HUMAN NECESSITIES HYGIENE MAGNETOTHERAPY MEDICAL OR VETERINARY SCIENCE RADIATION THERAPY ULTRASOUND THERAPY |
| title | Tuning mechanism for OAR and target objectives during optimization |
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