Aprepitant ready-to-use injection emulsion compositions

The present invention provides an emulsion composition comprising aprepitant for treatment of emesis. Particularly, the invention is a ready-to-use emulsion compositions comprising aprepitant and medium chain triglycerides for administration by intravenous infusion, wherein the emulsion composition...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Akasapu, Prem Sagar, Subramanian, Veerappan, Subramanian, Ilango
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention provides an emulsion composition comprising aprepitant for treatment of emesis. Particularly, the invention is a ready-to-use emulsion compositions comprising aprepitant and medium chain triglycerides for administration by intravenous infusion, wherein the emulsion composition is also free of ethanol. Further, the invention also provides processes of preparing such compositions and their use for the prevention and control of acute and delayed chemotherapy-induced nausea and vomiting, and/or for prevention of postoperative nausea and vomiting.