Device and methods for printing biological tissues and organs
Techniques for printing living tissues and organs are provided. An example apparatus includes a printing platform, bioink printing module with at least one nozzle designed for bioink dosing, a gel-forming composition printing module containing a UV-module, and a nozzle for dosing gel-forming composi...
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| creator | Mitryashkin, Alexandr Nikolaevich Novoselov, Sergei Vladimirovich Ostrovsky, Alexandr Yurievich Khesuani, Yusef Dzhordzhevich Mironov, Vladimir Alexandrovich Gladkaya, Irina Sergeevna |
| description | Techniques for printing living tissues and organs are provided. An example apparatus includes a printing platform, bioink printing module with at least one nozzle designed for bioink dosing, a gel-forming composition printing module containing a UV-module, and a nozzle for dosing gel-forming composition that starts polymerizing via UV radiation. A module is provided for relatively displacing the nozzles and/or the platform, in which the bioink printing module is separated from the gel-forming-composition printing module to prevent UV radiation from reaching the bioink printing module. The radiation is directed predominantly parallel to the printing platform to prevent UV radiation from reaching the biological tissues and/or organs being printed. A multi-functional device capable of combining various printing modes, providing a method of high-resolution printing of living tissues and organs based on UV-induced hydrogel polymerization, and a method of cell protection from UV radiation during the printing process, can be realized. |
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An example apparatus includes a printing platform, bioink printing module with at least one nozzle designed for bioink dosing, a gel-forming composition printing module containing a UV-module, and a nozzle for dosing gel-forming composition that starts polymerizing via UV radiation. A module is provided for relatively displacing the nozzles and/or the platform, in which the bioink printing module is separated from the gel-forming-composition printing module to prevent UV radiation from reaching the bioink printing module. The radiation is directed predominantly parallel to the printing platform to prevent UV radiation from reaching the biological tissues and/or organs being printed. 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| subjects | ADDITIVE MANUFACTURING TECHNOLOGY ADDITIVE MANUFACTURING, i.e. MANUFACTURING OFTHREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVEAGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING,STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PERFORMING OPERATIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TRANSPORTING VINEGAR WINE |
| title | Device and methods for printing biological tissues and organs |
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