Activation of bioluminescene by structural complementation

Provided herein are compositions and methods for the assembly of a bioluminescent complex from two or more non-luminescent (e.g., substantially non-luminescent) peptide and/or polypeptide units. In particular, bioluminescent activity is conferred upon a non-luminescent polypeptide via structural com...

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Hauptverfasser: Dart, Melanie, Goueli, Said, Unch, James, Dixon, Andrew S, Encell, Lance, Schwinn, Marie, Mondal, Subhanjan, Meisenheimer, Poncho, Robers, Matthew, Machleidt, Thomas, Nath, Nidhi, Binkowski, Brock F, Wood, Monika, Kirkland, Thomas, Hall, Mary, Zegzouti, Hicham, Pulukkunat, Dileep K, Wood, Keith
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creator Dart, Melanie
Goueli, Said
Unch, James
Dixon, Andrew S
Encell, Lance
Schwinn, Marie
Mondal, Subhanjan
Meisenheimer, Poncho
Robers, Matthew
Machleidt, Thomas
Nath, Nidhi
Binkowski, Brock F
Wood, Monika
Kirkland, Thomas
Hall, Mary
Zegzouti, Hicham
Pulukkunat, Dileep K
Wood, Keith
description Provided herein are compositions and methods for the assembly of a bioluminescent complex from two or more non-luminescent (e.g., substantially non-luminescent) peptide and/or polypeptide units. In particular, bioluminescent activity is conferred upon a non-luminescent polypeptide via structural complementation with another, complementary non-luminescent peptide.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
COMPOSITIONS THEREOF
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROCESSES OF PREPARING SUCH COMPOSITIONS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
TESTING
VINEGAR
WINE
title Activation of bioluminescene by structural complementation
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