Methods of improving accuracy and precision of droplet metering using an on-actuator reservoir as the fluid input

The present invention is directed to methods of improving accuracy of droplet metering using at least one on-actuator reservoir as the fluid input. In some embodiments, the on-actuator reservoir that is used for metering droplets includes a loading port, a liquid storage zone, a droplet metering zon...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yi, Uichong B, Srinivasan, Vijay
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention is directed to methods of improving accuracy of droplet metering using at least one on-actuator reservoir as the fluid input. In some embodiments, the on-actuator reservoir that is used for metering droplets includes a loading port, a liquid storage zone, a droplet metering zone, and a droplet dispensing zone. The on-actuator reservoirs are designed to prevent liquid flow-back into the loading port and to prevent liquid from flooding into the droplet operations gap in the dispensing zone.