Substituted dihydroimidazopyridinediones as MKNK1 and MKNK2 inhibitors

The present invention relates to substituted dihydroimidazopyridinedione compounds of general formula (I) as described and defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Schäcke, Heike, Panknin, Olaf, Menz, Stephan, Sülzle, Detlev, Klar, Ulrich, Bohlmann, Rolf
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to substituted dihydroimidazopyridinedione compounds of general formula (I) as described and defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyperproliferative, angiogenesis disorders, inflammatory diseases or diseases associated with inflammatory pain, as a sole agent or in combination with other active ingredients.