Antibody-sting agonist conjugates and their use in immunotherapy

The present disclosure relates to, among other things, antibody-drug conjugates comprising a STING agonist cyclic di-nucleotide conjugated to an antibody, preparation methods therefor, and uses therefor.

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Hauptverfasser: Wu, Youtong, Chen, Zhijian, Qiu, Jian, Wei, Qi, Shi, Heping, Chen, Chuo, Sun, Lijun
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creator Wu, Youtong
Chen, Zhijian
Qiu, Jian
Wei, Qi
Shi, Heping
Chen, Chuo
Sun, Lijun
description The present disclosure relates to, among other things, antibody-drug conjugates comprising a STING agonist cyclic di-nucleotide conjugated to an antibody, preparation methods therefor, and uses therefor.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Antibody-sting agonist conjugates and their use in immunotherapy
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