Pharmaceutical composition containing FGF21 mutant fusion protein and method for treating hepatitis, hepatic fibrosis, and hepatic cirrhosis

A fusion protein containing a biologically active protein and an FGF21 mutant protein, a pharmaceutical composition containing the fusion protein, and their uses are disclosed. The fusion protein and the pharmaceutical composition are effective in treating a liver disease including hepatitis, hepati...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Kim, Taewang, Oh, Se Woong, Kim, Jun Hwan, Song, Moo Young, Hong, Han Na, Choi, Hyun Ho, Kim, Jong Gyun, Kim, Dohoon
Format: Patent
Sprache:eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator Kim, Taewang
Oh, Se Woong
Kim, Jun Hwan
Song, Moo Young
Hong, Han Na
Choi, Hyun Ho
Kim, Jong Gyun
Kim, Dohoon
description A fusion protein containing a biologically active protein and an FGF21 mutant protein, a pharmaceutical composition containing the fusion protein, and their uses are disclosed. The fusion protein and the pharmaceutical composition are effective in treating a liver disease including hepatitis, hepatic fibrosis, and hepatic cirrhosis. The fusion protein has effects of inhibiting proliferation of inflammatory cells and fibroblasts, and thus can be effectively used for treating hepatitis, hepatic fibrosis, and hepatic cirrhosis.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US11179440B2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US11179440B2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US11179440B23</originalsourceid><addsrcrecordid>eNqNjrsKAjEQRbexEPUfxl7BrILYKq6WglovMTsxA5sHyexf-NEmsPZWczh37jDT6nMzMlqpcGBSsgflbfCJmLzL7FiSI_eG5tLUAuzA0jHoIZU4RM9IDqTrwCIb34H2ETii5NIxGDIwpdWICjS9Yr6eTSn9rKIYTdHzaqJln3Axzlm1bM6P03WNwbeYQn7TIbfPuxBif9jtNsd6-8_OF15pTiQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Pharmaceutical composition containing FGF21 mutant fusion protein and method for treating hepatitis, hepatic fibrosis, and hepatic cirrhosis</title><source>esp@cenet</source><creator>Kim, Taewang ; Oh, Se Woong ; Kim, Jun Hwan ; Song, Moo Young ; Hong, Han Na ; Choi, Hyun Ho ; Kim, Jong Gyun ; Kim, Dohoon</creator><creatorcontrib>Kim, Taewang ; Oh, Se Woong ; Kim, Jun Hwan ; Song, Moo Young ; Hong, Han Na ; Choi, Hyun Ho ; Kim, Jong Gyun ; Kim, Dohoon</creatorcontrib><description>A fusion protein containing a biologically active protein and an FGF21 mutant protein, a pharmaceutical composition containing the fusion protein, and their uses are disclosed. The fusion protein and the pharmaceutical composition are effective in treating a liver disease including hepatitis, hepatic fibrosis, and hepatic cirrhosis. The fusion protein has effects of inhibiting proliferation of inflammatory cells and fibroblasts, and thus can be effectively used for treating hepatitis, hepatic fibrosis, and hepatic cirrhosis.</description><language>eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20211123&amp;DB=EPODOC&amp;CC=US&amp;NR=11179440B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,782,887,25571,76555</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20211123&amp;DB=EPODOC&amp;CC=US&amp;NR=11179440B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Kim, Taewang</creatorcontrib><creatorcontrib>Oh, Se Woong</creatorcontrib><creatorcontrib>Kim, Jun Hwan</creatorcontrib><creatorcontrib>Song, Moo Young</creatorcontrib><creatorcontrib>Hong, Han Na</creatorcontrib><creatorcontrib>Choi, Hyun Ho</creatorcontrib><creatorcontrib>Kim, Jong Gyun</creatorcontrib><creatorcontrib>Kim, Dohoon</creatorcontrib><title>Pharmaceutical composition containing FGF21 mutant fusion protein and method for treating hepatitis, hepatic fibrosis, and hepatic cirrhosis</title><description>A fusion protein containing a biologically active protein and an FGF21 mutant protein, a pharmaceutical composition containing the fusion protein, and their uses are disclosed. The fusion protein and the pharmaceutical composition are effective in treating a liver disease including hepatitis, hepatic fibrosis, and hepatic cirrhosis. The fusion protein has effects of inhibiting proliferation of inflammatory cells and fibroblasts, and thus can be effectively used for treating hepatitis, hepatic fibrosis, and hepatic cirrhosis.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjrsKAjEQRbexEPUfxl7BrILYKq6WglovMTsxA5sHyexf-NEmsPZWczh37jDT6nMzMlqpcGBSsgflbfCJmLzL7FiSI_eG5tLUAuzA0jHoIZU4RM9IDqTrwCIb34H2ETii5NIxGDIwpdWICjS9Yr6eTSn9rKIYTdHzaqJln3Axzlm1bM6P03WNwbeYQn7TIbfPuxBif9jtNsd6-8_OF15pTiQ</recordid><startdate>20211123</startdate><enddate>20211123</enddate><creator>Kim, Taewang</creator><creator>Oh, Se Woong</creator><creator>Kim, Jun Hwan</creator><creator>Song, Moo Young</creator><creator>Hong, Han Na</creator><creator>Choi, Hyun Ho</creator><creator>Kim, Jong Gyun</creator><creator>Kim, Dohoon</creator><scope>EVB</scope></search><sort><creationdate>20211123</creationdate><title>Pharmaceutical composition containing FGF21 mutant fusion protein and method for treating hepatitis, hepatic fibrosis, and hepatic cirrhosis</title><author>Kim, Taewang ; Oh, Se Woong ; Kim, Jun Hwan ; Song, Moo Young ; Hong, Han Na ; Choi, Hyun Ho ; Kim, Jong Gyun ; Kim, Dohoon</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US11179440B23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2021</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>Kim, Taewang</creatorcontrib><creatorcontrib>Oh, Se Woong</creatorcontrib><creatorcontrib>Kim, Jun Hwan</creatorcontrib><creatorcontrib>Song, Moo Young</creatorcontrib><creatorcontrib>Hong, Han Na</creatorcontrib><creatorcontrib>Choi, Hyun Ho</creatorcontrib><creatorcontrib>Kim, Jong Gyun</creatorcontrib><creatorcontrib>Kim, Dohoon</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Kim, Taewang</au><au>Oh, Se Woong</au><au>Kim, Jun Hwan</au><au>Song, Moo Young</au><au>Hong, Han Na</au><au>Choi, Hyun Ho</au><au>Kim, Jong Gyun</au><au>Kim, Dohoon</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Pharmaceutical composition containing FGF21 mutant fusion protein and method for treating hepatitis, hepatic fibrosis, and hepatic cirrhosis</title><date>2021-11-23</date><risdate>2021</risdate><abstract>A fusion protein containing a biologically active protein and an FGF21 mutant protein, a pharmaceutical composition containing the fusion protein, and their uses are disclosed. The fusion protein and the pharmaceutical composition are effective in treating a liver disease including hepatitis, hepatic fibrosis, and hepatic cirrhosis. The fusion protein has effects of inhibiting proliferation of inflammatory cells and fibroblasts, and thus can be effectively used for treating hepatitis, hepatic fibrosis, and hepatic cirrhosis.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_epo_espacenet_US11179440B2
source esp@cenet
subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Pharmaceutical composition containing FGF21 mutant fusion protein and method for treating hepatitis, hepatic fibrosis, and hepatic cirrhosis
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-06T02%3A25%3A02IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Kim,%20Taewang&rft.date=2021-11-23&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS11179440B2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true