Angiotensin II receptor antagonist metabolite and NEP inhibitor composite and preparation method thereof

Angiotensin II receptor antagonist metabolite and NEP inhibitor composite and preparation method thereof

Provided are a supramolecular composite comprising an angiotensin II receptor (AT1) blocking compound, a neutral endopeptidase inhibitor (NEPi), and a pharmaceutically acceptable cation. The invention further provides a method for preparing the composite and an application of the composite for prepa...

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Hauptverfasser: Xu, Wenjie, Yan, Jie, Zheng, Yanxin, Wang, Yang, Li, Song, Zhi, Jianqiong
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Sprache:eng
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator Xu, Wenjie
Yan, Jie
Zheng, Yanxin
Wang, Yang
Li, Song
Zhi, Jianqiong
description Provided are a supramolecular composite comprising an angiotensin II receptor (AT1) blocking compound, a neutral endopeptidase inhibitor (NEPi), and a pharmaceutically acceptable cation. The invention further provides a method for preparing the composite and an application of the composite for preparing a pharmaceutical product for treating heart failure.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Angiotensin II receptor antagonist metabolite and NEP inhibitor composite and preparation method thereof
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