Fusions of antibodies to CD38 and attenuated interferon alpha

The present invention provides a polypeptide construct comprising a peptide or polypeptide signaling ligand linked to an antibody or antigen binding portion thereof which binds to a cell surface-associated antigen, wherein the ligand comprises at least one amino acid substitution or deletion which r...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	Wilson, Jr., David S, Tran, Stephen, Pogue, Sarah L, Pollard, Matthew, Taura, Tetsuya, Mikesell, Glen E, Doyle, Anthony G, Lin, Jack Tzu Chiao, Korver, Wouter, Clarke, Adam
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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