Delivery of drug nanoparticles and methods of use thereof

Disclosed are compositions and methods useful for enhancing the skin penetration of drug nanoparticles. The compositions can be hydrophobic and include a hydrophobic carrier, a volatile silicone fluid, and drug nanoparticles. Also disclosed are methods for inhibiting crystal growth of drug nanoparti...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Johnson, Keith, Maulhardt, Holly, Yang, Meidong, Lathrop, Robert, Franke, Roland
Format: Patent
Sprache:eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator Johnson, Keith
Maulhardt, Holly
Yang, Meidong
Lathrop, Robert
Franke, Roland
description Disclosed are compositions and methods useful for enhancing the skin penetration of drug nanoparticles. The compositions can be hydrophobic and include a hydrophobic carrier, a volatile silicone fluid, and drug nanoparticles. Also disclosed are methods for inhibiting crystal growth of drug nanoparticles in an aqueous carrier or a hydrophobic carrier. Further, methods to topically treat psoriasis using compositions containing nanoparticles of paclitaxel or other taxanes are disclosed.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US10918606B2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US10918606B2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US10918606B23</originalsourceid><addsrcrecordid>eNrjZLB0Sc3JLEstqlTIT1NIKSpNV8hLzMsvSCwqyUzOSS1WSMxLUchNLcnITykGqSgtTlUoyUgtSs1P42FgTUvMKU7lhdLcDIpuriHOHrqpBfnxqcUFicmpeakl8aHBhgaWhhZmBmZORsbEqAEAPgsuxg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Delivery of drug nanoparticles and methods of use thereof</title><source>esp@cenet</source><creator>Johnson, Keith ; Maulhardt, Holly ; Yang, Meidong ; Lathrop, Robert ; Franke, Roland</creator><creatorcontrib>Johnson, Keith ; Maulhardt, Holly ; Yang, Meidong ; Lathrop, Robert ; Franke, Roland</creatorcontrib><description>Disclosed are compositions and methods useful for enhancing the skin penetration of drug nanoparticles. The compositions can be hydrophobic and include a hydrophobic carrier, a volatile silicone fluid, and drug nanoparticles. Also disclosed are methods for inhibiting crystal growth of drug nanoparticles in an aqueous carrier or a hydrophobic carrier. Further, methods to topically treat psoriasis using compositions containing nanoparticles of paclitaxel or other taxanes are disclosed.</description><language>eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20210216&amp;DB=EPODOC&amp;CC=US&amp;NR=10918606B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20210216&amp;DB=EPODOC&amp;CC=US&amp;NR=10918606B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Johnson, Keith</creatorcontrib><creatorcontrib>Maulhardt, Holly</creatorcontrib><creatorcontrib>Yang, Meidong</creatorcontrib><creatorcontrib>Lathrop, Robert</creatorcontrib><creatorcontrib>Franke, Roland</creatorcontrib><title>Delivery of drug nanoparticles and methods of use thereof</title><description>Disclosed are compositions and methods useful for enhancing the skin penetration of drug nanoparticles. The compositions can be hydrophobic and include a hydrophobic carrier, a volatile silicone fluid, and drug nanoparticles. Also disclosed are methods for inhibiting crystal growth of drug nanoparticles in an aqueous carrier or a hydrophobic carrier. Further, methods to topically treat psoriasis using compositions containing nanoparticles of paclitaxel or other taxanes are disclosed.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLB0Sc3JLEstqlTIT1NIKSpNV8hLzMsvSCwqyUzOSS1WSMxLUchNLcnITykGqSgtTlUoyUgtSs1P42FgTUvMKU7lhdLcDIpuriHOHrqpBfnxqcUFicmpeakl8aHBhgaWhhZmBmZORsbEqAEAPgsuxg</recordid><startdate>20210216</startdate><enddate>20210216</enddate><creator>Johnson, Keith</creator><creator>Maulhardt, Holly</creator><creator>Yang, Meidong</creator><creator>Lathrop, Robert</creator><creator>Franke, Roland</creator><scope>EVB</scope></search><sort><creationdate>20210216</creationdate><title>Delivery of drug nanoparticles and methods of use thereof</title><author>Johnson, Keith ; Maulhardt, Holly ; Yang, Meidong ; Lathrop, Robert ; Franke, Roland</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US10918606B23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2021</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>Johnson, Keith</creatorcontrib><creatorcontrib>Maulhardt, Holly</creatorcontrib><creatorcontrib>Yang, Meidong</creatorcontrib><creatorcontrib>Lathrop, Robert</creatorcontrib><creatorcontrib>Franke, Roland</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Johnson, Keith</au><au>Maulhardt, Holly</au><au>Yang, Meidong</au><au>Lathrop, Robert</au><au>Franke, Roland</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Delivery of drug nanoparticles and methods of use thereof</title><date>2021-02-16</date><risdate>2021</risdate><abstract>Disclosed are compositions and methods useful for enhancing the skin penetration of drug nanoparticles. The compositions can be hydrophobic and include a hydrophobic carrier, a volatile silicone fluid, and drug nanoparticles. Also disclosed are methods for inhibiting crystal growth of drug nanoparticles in an aqueous carrier or a hydrophobic carrier. Further, methods to topically treat psoriasis using compositions containing nanoparticles of paclitaxel or other taxanes are disclosed.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_epo_espacenet_US10918606B2
source esp@cenet
subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Delivery of drug nanoparticles and methods of use thereof
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-25T02%3A42%3A44IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Johnson,%20Keith&rft.date=2021-02-16&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS10918606B2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true