Compounds and compositions for the inhibition of NAMPT

The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes. An illustrative compound of the invention is shown below:

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Hauptverfasser: Dragovich, Peter, Smith, Chase C, Bair, Kenneth W, Gosselin, Francis, Clodfelter, Karl H, Wang, Zhongguo, Reynolds, Dominic J, Han, Bingsong, Lin, Jian, Baumeister, Timm R, Buckmelter, Alexandre J, Yuen, Po-Wai, Roth, Bruce, Zheng, Xiaozhang
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creator Dragovich, Peter
Smith, Chase C
Bair, Kenneth W
Gosselin, Francis
Clodfelter, Karl H
Wang, Zhongguo
Reynolds, Dominic J
Han, Bingsong
Lin, Jian
Baumeister, Timm R
Buckmelter, Alexandre J
Yuen, Po-Wai
Roth, Bruce
Zheng, Xiaozhang
description The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes. An illustrative compound of the invention is shown below:
format Patent
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Compounds and compositions for the inhibition of NAMPT
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