Catalytic hydrogenation of nitriles

Catalytic hydrogenation of nitriles

The present invention relates to a novel catalytic hydrogenation of substituted 2-methyl cyanopyridyl derivatives, in particular 3-chloro-5-(trifluoromethyl)pyridin-2-yl]acetonitrile [=Py-CN] to substituted 2-ethylaminopyridine derivatives, in particular 2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]e...

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Hauptverfasser: Mueller, Thomas Norbert, Himmler, Thomas, Moradi, Wahed Ahmed
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CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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creator Mueller, Thomas Norbert
Himmler, Thomas
Moradi, Wahed Ahmed
description The present invention relates to a novel catalytic hydrogenation of substituted 2-methyl cyanopyridyl derivatives, in particular 3-chloro-5-(trifluoromethyl)pyridin-2-yl]acetonitrile [=Py-CN] to substituted 2-ethylaminopyridine derivatives, in particular 2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethanamine [=Py-ethanamine] or salts thereof in the presence of Raney catalysts, in particular Raney nickel or cobalt.
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HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title Catalytic hydrogenation of nitriles
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