Choroidal neovascularization suppressor or drusen formation suppressor, and method for assessing or screening for same

The existent therapeutic drugs for CNV are merely pharmaceuticals for a symptomatic therapy, and therapeutic drugs for radical cure are strongly demanded. Also, a therapeutic drug for Dry AMD does not exist, and therapeutic drugs for radical cure are strongly demanded. The present invention provides...

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Hauptverfasser: Mizunuma, Hidemi, Takai, Yoshihiro, Mitsuguchi, Yoko, Ogura, Dai, Kurose, Takahiro, Moriya, Mariyo, Arai, Yoko, Niwa, Shinichiro
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creator Mizunuma, Hidemi
Takai, Yoshihiro
Mitsuguchi, Yoko
Ogura, Dai
Kurose, Takahiro
Moriya, Mariyo
Arai, Yoko
Niwa, Shinichiro
description The existent therapeutic drugs for CNV are merely pharmaceuticals for a symptomatic therapy, and therapeutic drugs for radical cure are strongly demanded. Also, a therapeutic drug for Dry AMD does not exist, and therapeutic drugs for radical cure are strongly demanded. The present invention provides a prophylactic and/or therapeutic agent for choroidal neovascularization, containing a compound having an activity of suppressing epithelial-mesenchymal transition in retinal pigment epithelial cells, as an active ingredient. Also, the present invention provides a drusen suppressor comprising a compound having an activity of suppressing epithelial-mesenchymal transition in retinal pigment epithelial cells, as an active ingredient.
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subjects HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
TESTING
title Choroidal neovascularization suppressor or drusen formation suppressor, and method for assessing or screening for same
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