Use of histone acetyltransferase inhibitor amidoximes as anti-proliferative agents

Described herein is the use of bisamidoximes compounds for the treatment of cancer. In preferred embodiments, combinations of two or more bisamidoximes or combinations of a bisamidoxime and another anti-cancer agent were found to be effective against various types of cancer cells.

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Hauptverfasser: Gekombe, Amon, Johnson, James E, Dhanireddy, Sudheer, Dolliver, Debra, Bergel, Michael
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creator Gekombe, Amon
Johnson, James E
Dhanireddy, Sudheer
Dolliver, Debra
Bergel, Michael
description Described herein is the use of bisamidoximes compounds for the treatment of cancer. In preferred embodiments, combinations of two or more bisamidoximes or combinations of a bisamidoxime and another anti-cancer agent were found to be effective against various types of cancer cells.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Use of histone acetyltransferase inhibitor amidoximes as anti-proliferative agents
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