Anti-cancer compounds and conjugates thereof

Disclosed are compounds based on dolastatins, drug-conjugates, methods of preparing drug-conjugates, and uses thereof. Also disclosed are pharmaceutical compositions and methods of treatment. The compounds and drug-conjugates disclosed herein can be used to treat diseases such as bladder cancer, bre...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	Cohen, Steven Bruce, Lee, Bryan Junn, Vining, Oliver Booth, Stout, Elizabeth Paige, Esquenazi, Eduardo, Usui, Ippei, Macherla, Venkata Rami Reddy, Schammel, Alexander Wayne, Beverage, Jacob Neal
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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