Microfluidic device for characterzing polynucleotides

A microfluidic sequencing device in which a stream of microdroplets at least some of which contain a single nucleotide base are made to undergo reaction with a capture system to capture and detect an ordered sequence of single nucleotide bases generated by progressive pyrophosphorolysis.

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Hauptverfasser: Amasio, Michele, Balmforth, Barnaby, Breiner, Boris, Dear, Paul, Isaac, Thomas Henry, Soares, Bruno Flavio Nogueira de Sousa, Frayling, Cameron Alexander, Natale, Alessandra
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creator Amasio, Michele
Balmforth, Barnaby
Breiner, Boris
Dear, Paul
Isaac, Thomas Henry
Soares, Bruno Flavio Nogueira de Sousa
Frayling, Cameron Alexander
Natale, Alessandra
description A microfluidic sequencing device in which a stream of microdroplets at least some of which contain a single nucleotide base are made to undergo reaction with a capture system to capture and detect an ordered sequence of single nucleotide bases generated by progressive pyrophosphorolysis.
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subjects BEER
BIOCHEMISTRY
CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
PHYSICS
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
TESTING
TRANSPORTING
VINEGAR
WINE
title Microfluidic device for characterzing polynucleotides
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