Solid oral film dosage forms and methods for making same

Oral film dosage forms that provide improved solubilization and stabilization of an active ingredient in particle form include at least one primary crystallization inhibitor in an amount that inhibits growth and/or agglomeration of the active ingredient, a polyoxyethylated fatty acid glycerides in a...

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Hauptverfasser: Paiement, Nadine, Rodes, Laetitia, Tir, Billal, Zerbe, Horst G, Long, Cormac, Angusti, Angela, Obeid, Rodolphe
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creator Paiement, Nadine
Rodes, Laetitia
Tir, Billal
Zerbe, Horst G
Long, Cormac
Angusti, Angela
Obeid, Rodolphe
description Oral film dosage forms that provide improved solubilization and stabilization of an active ingredient in particle form include at least one primary crystallization inhibitor in an amount that inhibits growth and/or agglomeration of the active ingredient, a polyoxyethylated fatty acid glycerides in an amount that further enhances inhibition of crystallization, growth and agglomeration of the particles of the pharmaceutically active ingredient; and at least one plasticizer present in an amount that is effective to increase flexibility and elasticity of the film dosage form.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Solid oral film dosage forms and methods for making same
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