Bifunctional polypeptides

A bifunctional polypeptide comprising a specific binding partner for a peptide-MHC epitope, such as an antibody or T cell receptor, and an immune effector, such as an antibody or a cytokine, the immune effector part being linked to the N-terminus of the peptide-MHC binding part.

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Bibliographische Detailangaben
Hauptverfasser: Vuidepot, Annelise Brigitte, Jakobsen, Bent Karsten, Li, Yi
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A bifunctional polypeptide comprising a specific binding partner for a peptide-MHC epitope, such as an antibody or T cell receptor, and an immune effector, such as an antibody or a cytokine, the immune effector part being linked to the N-terminus of the peptide-MHC binding part.