Methods for accurate sequence data and modified base position determination

Disclosed herein are methods of determining the sequence and/or positions of modified bases in a nucleic acid sample present in a circular molecule with a nucleic acid insert of known sequence comprising obtaining sequence data of at least two insert-sample units. In some embodiments, the methods co...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fann, Jenn-Yeh, Chen, Hui-Ling, Chiou, Chung-Fan, Pan, Chao-Chi, Chien, Hung-Chi
Format: Patent
Sprache:eng
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