Image reconstruction system, method, and computer program

The present invention relates to an image reconstruction system for statistically reconstructing images from transmission measurements. The image reconstruction system comprises an update equation providing unit for providing an update equation based on an iterative statistical model. The update equation comprises a data term and a regularization term. The invention proposes to not modify the regularization term, but rather the weights with which individual measurements contribute are modified on a per image voxel and per measurement basis. This is achieved by modifying the contributions of each measurement by including an additional weight on a per image voxel/per measurement basis. The additional weight for each measurement is determined by calculating the noise perpendicular to each measurement ray at each voxel position and a voxel and measurement dependent weight for each measurement, and integrated into the update equation's data term.