Engineered beta-subunit of tryptophan synthase for production of non-canonical amino acids

This disclosure relates to modified tryptophan synthase and more particularly to modified beta-subunits of tryptophan synthase. The disclosure further relates to cells expressing such modified subunits and methods of producing non-canonical amino acids.

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Hauptverfasser: Romney, David K, Buller, Andrew Richard, van Roye, Paul, Brinkmann-Chen, Sabine, Herger, Michael, Calles, Javier Murciano
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creator Romney, David K
Buller, Andrew Richard
van Roye, Paul
Brinkmann-Chen, Sabine
Herger, Michael
Calles, Javier Murciano
description This disclosure relates to modified tryptophan synthase and more particularly to modified beta-subunits of tryptophan synthase. The disclosure further relates to cells expressing such modified subunits and methods of producing non-canonical amino acids.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title Engineered beta-subunit of tryptophan synthase for production of non-canonical amino acids
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