Pharmaceutical composition containing clomipramine and preparation method therefor

Pharmaceutical composition containing clomipramine and preparation method therefor

The present invention provides a pharmaceutical formulation comprising clomipramine or its pharmaceutically acceptable salt (preferably, clomipramine hydrochloride) as the first active ingredient, and sildenafil or its pharmaceutically acceptable salt (preferably, sildenafil citrate) as the second a...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Lee, Bong-Sang, Kim, Jung-Hwa, Lee, Dong-Jin, Park, Hyun-Jung, Kwak, Seong-Shin, Jeon, Hong Ryeol
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator Lee, Bong-Sang
Kim, Jung-Hwa
Lee, Dong-Jin
Park, Hyun-Jung
Kwak, Seong-Shin
Jeon, Hong Ryeol
description The present invention provides a pharmaceutical formulation comprising clomipramine or its pharmaceutically acceptable salt (preferably, clomipramine hydrochloride) as the first active ingredient, and sildenafil or its pharmaceutically acceptable salt (preferably, sildenafil citrate) as the second active ingredient, wherein stability of clomipramine is improved, and a method for manufacturing this pharmaceutical formulation. In particular, the present invention provides a pharmaceutical formulation comprising the above two active ingredients and manufactured by using a wet granulation method, wherein stability of clomipramine is improved, and a method for manufacturing this pharmaceutical formulation.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US10512610B2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US10512610B2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US10512610B23</originalsourceid><addsrcrecordid>eNqNjUsKwjAQQLtxIeod4gGEpqIHUBSX4mddhnRqBpKZMBnvbxEP4Oq9xYM3b27XCJoh4NsoQHJBcpFKRsKTswEx8cuFJJmKQiZGBzy4olhA4dtltCiDs4iKo-iymY2QKq5-XDTr8-lxvGywSI-1TDNG65933-58t_ftodv-03wAxOc5Zg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Pharmaceutical composition containing clomipramine and preparation method therefor</title><source>esp@cenet</source><creator>Lee, Bong-Sang ; Kim, Jung-Hwa ; Lee, Dong-Jin ; Park, Hyun-Jung ; Kwak, Seong-Shin ; Jeon, Hong Ryeol</creator><creatorcontrib>Lee, Bong-Sang ; Kim, Jung-Hwa ; Lee, Dong-Jin ; Park, Hyun-Jung ; Kwak, Seong-Shin ; Jeon, Hong Ryeol</creatorcontrib><description>The present invention provides a pharmaceutical formulation comprising clomipramine or its pharmaceutically acceptable salt (preferably, clomipramine hydrochloride) as the first active ingredient, and sildenafil or its pharmaceutically acceptable salt (preferably, sildenafil citrate) as the second active ingredient, wherein stability of clomipramine is improved, and a method for manufacturing this pharmaceutical formulation. In particular, the present invention provides a pharmaceutical formulation comprising the above two active ingredients and manufactured by using a wet granulation method, wherein stability of clomipramine is improved, and a method for manufacturing this pharmaceutical formulation.</description><language>eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2019</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20191224&amp;DB=EPODOC&amp;CC=US&amp;NR=10512610B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20191224&amp;DB=EPODOC&amp;CC=US&amp;NR=10512610B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Lee, Bong-Sang</creatorcontrib><creatorcontrib>Kim, Jung-Hwa</creatorcontrib><creatorcontrib>Lee, Dong-Jin</creatorcontrib><creatorcontrib>Park, Hyun-Jung</creatorcontrib><creatorcontrib>Kwak, Seong-Shin</creatorcontrib><creatorcontrib>Jeon, Hong Ryeol</creatorcontrib><title>Pharmaceutical composition containing clomipramine and preparation method therefor</title><description>The present invention provides a pharmaceutical formulation comprising clomipramine or its pharmaceutically acceptable salt (preferably, clomipramine hydrochloride) as the first active ingredient, and sildenafil or its pharmaceutically acceptable salt (preferably, sildenafil citrate) as the second active ingredient, wherein stability of clomipramine is improved, and a method for manufacturing this pharmaceutical formulation. In particular, the present invention provides a pharmaceutical formulation comprising the above two active ingredients and manufactured by using a wet granulation method, wherein stability of clomipramine is improved, and a method for manufacturing this pharmaceutical formulation.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2019</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjUsKwjAQQLtxIeod4gGEpqIHUBSX4mddhnRqBpKZMBnvbxEP4Oq9xYM3b27XCJoh4NsoQHJBcpFKRsKTswEx8cuFJJmKQiZGBzy4olhA4dtltCiDs4iKo-iymY2QKq5-XDTr8-lxvGywSI-1TDNG65933-58t_ftodv-03wAxOc5Zg</recordid><startdate>20191224</startdate><enddate>20191224</enddate><creator>Lee, Bong-Sang</creator><creator>Kim, Jung-Hwa</creator><creator>Lee, Dong-Jin</creator><creator>Park, Hyun-Jung</creator><creator>Kwak, Seong-Shin</creator><creator>Jeon, Hong Ryeol</creator><scope>EVB</scope></search><sort><creationdate>20191224</creationdate><title>Pharmaceutical composition containing clomipramine and preparation method therefor</title><author>Lee, Bong-Sang ; Kim, Jung-Hwa ; Lee, Dong-Jin ; Park, Hyun-Jung ; Kwak, Seong-Shin ; Jeon, Hong Ryeol</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US10512610B23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2019</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>Lee, Bong-Sang</creatorcontrib><creatorcontrib>Kim, Jung-Hwa</creatorcontrib><creatorcontrib>Lee, Dong-Jin</creatorcontrib><creatorcontrib>Park, Hyun-Jung</creatorcontrib><creatorcontrib>Kwak, Seong-Shin</creatorcontrib><creatorcontrib>Jeon, Hong Ryeol</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Lee, Bong-Sang</au><au>Kim, Jung-Hwa</au><au>Lee, Dong-Jin</au><au>Park, Hyun-Jung</au><au>Kwak, Seong-Shin</au><au>Jeon, Hong Ryeol</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Pharmaceutical composition containing clomipramine and preparation method therefor</title><date>2019-12-24</date><risdate>2019</risdate><abstract>The present invention provides a pharmaceutical formulation comprising clomipramine or its pharmaceutically acceptable salt (preferably, clomipramine hydrochloride) as the first active ingredient, and sildenafil or its pharmaceutically acceptable salt (preferably, sildenafil citrate) as the second active ingredient, wherein stability of clomipramine is improved, and a method for manufacturing this pharmaceutical formulation. In particular, the present invention provides a pharmaceutical formulation comprising the above two active ingredients and manufactured by using a wet granulation method, wherein stability of clomipramine is improved, and a method for manufacturing this pharmaceutical formulation.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_epo_espacenet_US10512610B2
source esp@cenet
subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Pharmaceutical composition containing clomipramine and preparation method therefor
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-18T03%3A46%3A33IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Lee,%20Bong-Sang&rft.date=2019-12-24&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS10512610B2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true