Tricyclic compounds as inhibitors of mutant IDH enzymes

The present invention is directed to tricyclic compounds of formula (I) which are inhibitors of one or more mutant IDH enzymes (I); wherein A is -C(R1)= or -N=; and X is selected from the group consisting of: (II-i), and (II-ii). The present invention is also directed to uses of the tricyclic compou...

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Hauptverfasser:	Sciammetta, Nunzio, Reutershan, Michael H, Fischer, Christian, Ellis, J. Michael, Gibeau, Craig R, Wu, Zhicai, Kim, Alexander J, Bogen, Stephane L, Shao, Pengcheng P, Fradera Llinas, Francesc Xavier, Parker, Jr., Dann L, Esposite, Sara, Sun, Wanying, Hoffman, Dawn M, Huang, Chunhui, Lampe, John W, Machacek, Michelle R, Yu, Yang, Childers, Matthew L, Sloman, David L, Kattar, Solomon D, Ujjainwalla, Feroze, McMasters, Daniel R
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
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