Method, substrate and device for separating nucleic acids

A method is provided herein, the method includes: applying a sample comprising target nucleic acids to a sample application zone of a substrate; and flowing a nucleic acid amplification reaction mixture across a length of the substrate through the sample application zone to amplify the target nuclei...

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Hauptverfasser: Nelson, John Richard, Spooner, Patrick McCoy, Duthie, Robert Scott, Watkins, Vicki Herzl, Misner, Matthew Jeremiah, Burns, Andrew Arthur Paul, Grossmann, Gregory Andrew, Dees, Elizabeth Marie, Kvam, Erik Leeming, Moore, David Roger
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creator Nelson, John Richard
Spooner, Patrick McCoy
Duthie, Robert Scott
Watkins, Vicki Herzl
Misner, Matthew Jeremiah
Burns, Andrew Arthur Paul
Grossmann, Gregory Andrew
Dees, Elizabeth Marie
Kvam, Erik Leeming
Moore, David Roger
description A method is provided herein, the method includes: applying a sample comprising target nucleic acids to a sample application zone of a substrate; and flowing a nucleic acid amplification reaction mixture across a length of the substrate through the sample application zone to amplify the target nucleic acid forming a nucleic acid amplification product; wherein the target nucleic acid having a first molecular weight is substantially immobilized at the sample application zone and wherein the amplification product having a second molecular weight migrates away from the sample application zone. An associated device is also provided.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title Method, substrate and device for separating nucleic acids
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