Monobactam organic compounds for the treatment of bacterial infections

Monobactam organic compounds for the treatment of bacterial infections

This invention pertains generally to antibacterial compounds of Formula I,as further described herein, and pharmaceutically acceptable salts and formulations thereof. In certain aspects, the invention pertains to methods of using such compounds to treat infections such as those caused by Gram-negati...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yifru, Aregahegn, Lin, Xiaodong, Simmons, Robert Lowell, Lindvall, Mika, Zhu, Qingming, Casarez, Anthony, Reck, Folkert, McEnroe, Glenn, Tjandra, Meiliana, Aulakh, Virender Singh, Moser, Heinz Ernst
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:This invention pertains generally to antibacterial compounds of Formula I,as further described herein, and pharmaceutically acceptable salts and formulations thereof. In certain aspects, the invention pertains to methods of using such compounds to treat infections such as those caused by Gram-negative bacteria.