Magnetic capture of a target from a fluid

Disclosed herein is an improved method for magnetic capture of target molecules (e.g., microbes) in a fluid. Kits and solid substrates for carrying the method described herein are also provided. In some embodiments, the methods, kits, and solid substrates described herein are optimized for separatio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kang, Joo Hun, Ingber, Donald E, Super, Michael
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Disclosed herein is an improved method for magnetic capture of target molecules (e.g., microbes) in a fluid. Kits and solid substrates for carrying the method described herein are also provided. In some embodiments, the methods, kits, and solid substrates described herein are optimized for separation and/or detection of microbes and microbe-associated molecular pattern (MAMP) (including, e.g., but not limited to, a cell component of microbes, lipopolysaccharides (LPS), and/or endotoxin).