IRE-1α inhibitors

Compounds which directly inhibit IRE-1α activity in vitro, prodrugs, and pharmaceutically acceptable salts thereof. Such compounds and prodrugs are useful for treating diseases associated with the unfolded protein response or with regulated IRE1-dependent decay (RIDD) and can be used as single agent...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	Yang, Yun, Zeng, Qingping, Patterson, John Bruce, Zubovics, Zoltan, Wade, Warren Stanfield, Toro, Andras, Wu, Zhipeng
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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