Process for preparing a powder comprising a human coagulation factor protein and a lactic acid polymer

Process for preparing a powder comprising a human coagulation factor protein and a lactic acid polymer

A process for preparing a powder, which includes one or more human coagulation factor proteins and a lactic acid polymer, involves mixing and dispersing a lactic acid polymer with a particle size d50 in the range 0.1-2 μm and the one or more human coagulation factor proteins in water. The dispersion...

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Hauptverfasser: Ullrich, Susanne, Engel, Andrea, Daufenbach, Jens, Germer, Matthias, Kistner, Steffen, Benedikt, Anne, Tome-Alcalde, Juan, Tice, Tom, Liefke, Melanie, Müller-Albers, Jessica, Windhab, Norbert
Format: Patent
Sprache:eng
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator Ullrich, Susanne
Engel, Andrea
Daufenbach, Jens
Germer, Matthias
Kistner, Steffen
Benedikt, Anne
Tome-Alcalde, Juan
Tice, Tom
Liefke, Melanie
Müller-Albers, Jessica
Windhab, Norbert
description A process for preparing a powder, which includes one or more human coagulation factor proteins and a lactic acid polymer, involves mixing and dispersing a lactic acid polymer with a particle size d50 in the range 0.1-2 μm and the one or more human coagulation factor proteins in water. The dispersion is dried, and the resulting dried mass is compressed. The resulting compressed dried mass is comminuted to a powder with a particle size d50 in the range of more than 0.5 and up to 5 μm.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Process for preparing a powder comprising a human coagulation factor protein and a lactic acid polymer
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